NEUROG1; BHLHA6; NEUROD3; NGN; NGN1; Neurogenin-1; Class A basic helix-loop-helix protein 6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
BHLHA6 NEUROD3 NGN NGN1
Alternative Names
NEUROG1 BHLHA6 NEUROD3 NGN NGN1 Neurogenin-1 Class A basic helix-loop-helix protein 6 Neurogenic basic-helix-loop-helix protein Neurogenic differentiation factor 3
Molecular Weight(MW)
25718 Da
Function
Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity)
Tissue Specificity
Expression restricted to the embryonic nervous system
Western blot analysis of hNeuroG1-F217 in Jurkat cell line lysates (35ug/lane). NEUROG1 (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.