Application
NFKBIL2 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the NFKBIL2 antibody detected the NFKBIL2 protein (arrow).| Product Name | NFKBIL2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TONSL; IKBR; NFKBIL2; Tonsoku-like protein; Inhibitor of kappa B-related protein; NF-kappa-B inhibitor-like protein 2; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IKBR NFKBIL2 |
|---|---|
| Alternative Names | TONSL IKBR NFKBIL2 Tonsoku-like protein Inhibitor of kappa B-related protein NF-kappa-B inhibitor-like protein 2 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2 |
| Molecular Weight(MW) | 150929 Da |
| Function | Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork- associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold |
| Tissue Specificity | Expressed in heart, skeletal muscle and tracheal epithelial cells |
| Cellular Localization | Cytoplasm. Nucleus. Note=Mainly nuclear. Localizes to DNA damage sites, accumulates at stressed replication forks |
| Entrez Gene | 4796 |
|---|---|
| Nucleotide Accession | NP_038460.4 |
Application
NFKBIL2 Antibody (N-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the NFKBIL2 antibody detected the NFKBIL2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
