Application
Western blot analysis of NFKBIB Antibody (C-term) in A2058 cell line lysates (35ug/lane). NFKBIB (arrow) was detected using the purified Pab.| Product Name | NFKBIB Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IKBB, TRIP9 |
|---|---|
| Alternative Names | NFKBIB IKBB TRIP9 NF-kappa-B inhibitor beta I-kappa-B-beta Thyroid receptor-interacting protein 9 |
| Molecular Weight(MW) | 37771 Da |
| Function | Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation |
| Tissue Specificity | Expressed in all tissues examined. |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity) |
| Entrez Gene | 4793 |
|---|
Application
Western blot analysis of NFKBIB Antibody (C-term) in A2058 cell line lysates (35ug/lane). NFKBIB (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
