Application
Western blot analysis of anti-HGK Antibody (C-term) in jurkat cell line lysates (35ug/lane). HGK(arrow) was detected using the purified Pab.| Product Name | NIK Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HGK, KIAA0687, NIK |
|---|---|
| Alternative Names | MAP4K4 HGK KIAA0687 NIK Mitogen-activated protein kinase kinase kinase kinase 4 HPK/GCK-like kinase HGK MAPK/ERK kinase kinase kinase 4 Nck-interacting kinase |
| Molecular Weight(MW) | 142101 Da |
| Function | Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha Appears to act upstream of the JUN N-terminal pathway Phosphorylates SMAD1 on Thr-322 |
| Tissue Specificity | Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 9448 |
|---|
Application
Western blot analysis of anti-HGK Antibody (C-term) in jurkat cell line lysates (35ug/lane). HGK(arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
