Application
NIT1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the NIT1 antibody detected the NIT1 protein (arrow).| Product Name | NIT1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | NIT1 Nitrilase homolog 1 |
|---|---|
| Molecular Weight(MW) | 35896 Da |
| Function | Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2 (By similarity) |
| Tissue Specificity | Detected in heart, brain, placenta, liver, skeletal muscle, kidney and pancreas |
| Cellular Localization | Cytoplasm. Mitochondrion (By similarity). |
| Entrez Gene | 4817 |
|---|---|
| Nucleotide Accession | NP_001172023.1 NP_005591.1 NP_001172022.1 NP_001172021.1 |
Application
NIT1 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the NIT1 antibody detected the NIT1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
