Application
NKIRAS1 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the NKIRAS1 antibody detected the NKIRAS1 protein (arrow).| Product Name | NKIRAS1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KBRAS1 |
|---|---|
| Alternative Names | NKIRAS1 KBRAS1 NF-kappa-B inhibitor-interacting Ras-like protein 1 I-kappa-B-interacting Ras-like protein 1 |
| Molecular Weight(MW) | 21643 Da |
| Function | Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 28512 |
|---|---|
| Nucleotide Accession | NP_065078.1 |
Application
NKIRAS1 Antibody (Center) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the NKIRAS1 antibody detected the NKIRAS1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
