Application
NKG2D Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NKG2D antibody detected the NKG2D protein (arrow).| Product Name | NKG2D Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | D12S2489E, NKG2D |
|---|---|
| Alternative Names | KLRK1 D12S2489E NKG2D NKG2-D type II integral membrane protein Killer cell lectin-like receptor subfamily K member 1 NK cell receptor D NKG2-D-activating NK receptor CD_antigen=CD314 |
| Molecular Weight(MW) | 25274 Da |
| Function | Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes |
| Tissue Specificity | Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs) |
| Cellular Localization | Membrane; Single-pass type II membrane protein |
| Entrez Gene | 22914 |
|---|---|
| Nucleotide Accession | NP_031386.2 |
Application
NKG2D Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NKG2D antibody detected the NKG2D protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
