Application
NKX2-1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the NKX2-1 antibody detected the NKX2-1 protein (arrow).| Product Name | NKX2-1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NKX2A, TITF1, TTF1 |
|---|---|
| Alternative Names | NKX2-1 NKX2A TITF1 TTF1 Homeobox protein Nkx-2.1 Homeobox protein NK-2 homolog A Thyroid nuclear factor 1 Thyroid transcription factor 1 |
| Molecular Weight(MW) | 38596 Da |
| Function | Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis |
| Tissue Specificity | Thyroid and lung. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 7080 |
|---|---|
| Nucleotide Accession | NP_003308.1 |
Application
NKX2-1 Antibody (Center) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the NKX2-1 antibody detected the NKX2-1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
