Application
NKX2-2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NKX2-2 antibody detected the NKX2-2 protein (arrow).| Product Name | NKX2-2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NKX2.2, NKX2B |
|---|---|
| Alternative Names | NKX2-2 NKX2.2 NKX2B Homeobox protein Nkx-2.2 Homeobox protein NK-2 homolog B |
| Molecular Weight(MW) | 30133 Da |
| Function | Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity) |
| Tissue Specificity | This NKX2-2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-128 amino acids from the Central region of human NKX2-2. |
| Cellular Localization | Nucleus (By similarity). |
| Entrez Gene | 4821 |
|---|---|
| Nucleotide Accession | NP_002500.1 |
Application
NKX2-2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NKX2-2 antibody detected the NKX2-2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
