Application
NLRP12/MB10187 antibody (Cat. #AM1894b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the NLRP12/MB10187 antibody detected the NLRP12/MB10187 protein (arrow).| Product Name | NLRP12 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgM |
| Clone Number | 228CT4.1.3 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500~1500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NALP12, PYPAF7, RNO |
|---|---|
| Alternative Names | NLRP12 NALP12 PYPAF7 RNO NACHT LRR and PYD domains-containing protein 12 Monarch-1 PYRIN-containing APAF1-like protein 7 Regulated by nitric oxide |
| Molecular Weight(MW) | 120173 Da |
| Function | May mediate activation of CASP1 via ASC and promote activation of NF-kappa-B via IKK |
| Tissue Specificity | Detected only in peripheral blood leukocytes, predominantly in eosinophils and granulocytes, and at lower levels in monocytes |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 91662 |
|---|---|
| Nucleotide Accession | NP_150639.1 NP_653288.1 |
Application
NLRP12/MB10187 antibody (Cat. #AM1894b) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the NLRP12/MB10187 antibody detected the NLRP12/MB10187 protein (arrow).| Application Notes | WB:1:500~1500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
