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NME5 Antibody (Center)

Catalog Number:OM215455
OM215455
Discount Price
OM215455-100ul
1~2 Week
100ul
OM215455-50ul
50ul
OM215455-20ul
20ul
1~2 Week
Product Profile
Product Name NME5 Antibody (Center)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHCWB
IHC:1:50~100 WB
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names NME5
Nucleoside diphosphate kinase homolog 5
Inhibitor of p53-induced apoptosis-beta
Testis-specific nm23 homolog
nm23-H5
Molecular Weight(MW) 24236 Da
Function Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species (By similarity)
Tissue Specificity Specifically expressed in testis germinal cells
Database Links
Entrez Gene 8382
Application

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Application

NME5 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NME5 antibody detected the NME5 protein (arrow).
Application Notes IHC:1:50~100 WB
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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