Application
NPLOC4 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NPLOC4 antibody detected the NPLOC4 protein (arrow).| Product Name | NPLOC4 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1499, NPL4 |
|---|---|
| Alternative Names | NPLOC4 KIAA1499 NPL4 Nuclear protein localization protein 4 homolog |
| Molecular Weight(MW) | 68120 Da |
| Function | The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity) |
| Tissue Specificity | Expressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver |
| Cellular Localization | Cytoplasm, cytosol (By similarity). Endoplasmic reticulum (By similarity). Nucleus (By similarity) Note=Associated with the endoplasmic reticulum and nuclear (By similarity) |
| Entrez Gene | 55666 |
|---|---|
| Nucleotide Accession | NP_060391.2 |
Application
NPLOC4 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NPLOC4 antibody detected the NPLOC4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
