NPNT Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the NPNT antibody detected the NPNT protein (arrow).
NPNT; EGFL6L; POEM; Nephronectin; Preosteoblast EGF-like repeat protein with MAM domain; Protein EGFL6-like
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
EGFL6L POEM
Alternative Names
NPNT EGFL6L POEM Nephronectin Preosteoblast EGF-like repeat protein with MAM domain Protein EGFL6-like
Molecular Weight(MW)
61907 Da
Function
Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha- 8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity)
Tissue Specificity
Expressed in kidney and lung and to a lower extent in brain, pregnant uterus, placenta, thyroid gland and blood vessels
Cellular Localization
Secreted, extracellular space, extracellular matrix (By similarity). Note=Trapped on the cell surface or in the extracellular matrix (By similarity)
NPNT Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the NPNT antibody detected the NPNT protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.