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NPPC Antibody (C-term)

Catalog Number:OM215579
OM215579
Discount Price
OM215579-100ul
1~2 Week
100ul
OM215579-50ul
50ul
OM215579-20ul
20ul
1~2 Week
Product Profile
Product Name NPPC Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias NPPC; CNP2; C-type natriuretic peptide; CNP-22; CNP-29; CNP-53
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms CNP2
Alternative Names NPPC
CNP2
C-type natriuretic peptide
CNP-22
CNP-29
CNP-53
Molecular Weight(MW) 13246 Da
Function Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation. May also be vasoactive and natriuretic. Specifically binds and stimulates the cGMP production of the NPR2 receptor. Binds the clearance receptor NPR3 (By similarity)
Tissue Specificity This NPPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-109 amino acids from the C-terminal region of human NPPC.
Cellular Localization Secreted.
Database Links
Entrez Gene 4880
Nucleotide Accession NP_077720.1
Application

Application

NPPC Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NPPC antibody detected the NPPC protein (arrow).

Application

NPPC Antibody (C-term) (AP14031b)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NPPC Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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