Application
NPRL2 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NPRL2 antibody detected the NPRL2 protein (arrow).| Product Name | NPRL2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NPRL2; TUSC4; Nitrogen permease regulator 2-like protein; Gene 21 protein; Tumor suppressor candidate 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TUSC4 |
|---|---|
| Alternative Names | NPRL2 TUSC4 Nitrogen permease regulator 2-like protein Gene 21 protein Tumor suppressor candidate 4 |
| Molecular Weight(MW) | 43658 Da |
| Function | Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down-regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr-9 Tyr-373 and Tyr-376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs |
| Tissue Specificity | Most abundant in skeletal muscle, followed by brain, liver and pancreas, with lower amounts in lung, kidney, placenta and heart. Expressed in most lung cancer cell lines tested |
| Entrez Gene | 10641 |
|---|---|
| Nucleotide Accession | NP_006536.3 |
Application
NPRL2 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NPRL2 antibody detected the NPRL2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
