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NR0B1 Antibody (Center)

Catalog Number:OM215606
OM215606
Discount Price
OM215606-100ul
1~2 Week
100ul
OM215606-50ul
50ul
OM215606-20ul
20ul
1~2 Week
Product Profile
Product Name NR0B1 Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias NR0B1; AHC; DAX1; Nuclear receptor subfamily 0 group B member 1; DSS-AHC critical region on the X chromosome protein 1; Nuclear receptor DAX-1
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms AHC
DAX1
Alternative Names NR0B1
AHC
DAX1
Nuclear receptor subfamily 0 group B member 1
DSS-AHC critical region on the X chromosome protein 1
Nuclear receptor DAX-1
Molecular Weight(MW) 51718 Da
Function Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency (By similarity)
Tissue Specificity This NR0B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-333 amino acids from the Central region of human NR0B1.
Cellular Localization Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and nucleus. Homodimers exits in the cytoplasm and in the nucleus
Database Links
Entrez Gene 190
Nucleotide Accession NP_000466.2
Application

Application

NR0B1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NR0B1 antibody detected the NR0B1 protein (arrow).

Application

Western blot analysis of NR0B1 (arrow) using rabbit polyclonal NR0B1 Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the NR0B1 gene.

Application

NR0B1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NR0B1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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