Application
NR1I3 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NR1I3 antibody detected the NR1I3 protein (arrow).| Product Name | NR1I3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR1I3; CAR; Nuclear receptor subfamily 1 group I member 3; Constitutive activator of retinoid response; Constitutive androstane receptor; Orphan nuclear receptor MB67 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAR |
|---|---|
| Alternative Names | NR1I3 CAR Nuclear receptor subfamily 1 group I member 3 Constitutive activator of retinoid response Constitutive androstane receptor Orphan nuclear receptor MB67 |
| Molecular Weight(MW) | 39942 Da |
| Function | Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element |
| Tissue Specificity | Predominantly expressed in liver. |
| Cellular Localization | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Note=Recruited to the cytoplasm by DNAJC7 (By similarity) |
| Entrez Gene | 9970 |
|---|---|
| Nucleotide Accession | NP_005113.1 NP_001070948.1 |
Application
NR1I3 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the NR1I3 antibody detected the NR1I3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
