Application
NR2E3 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the NR2E3 antibody detected the NR2E3 protein (arrow).| Product Name | NR2E3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR2E3; PNR; RNR; Photoreceptor-specific nuclear receptor; Nuclear receptor subfamily 2 group E member 3; Retina-specific nuclear receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PNR RNR |
|---|---|
| Alternative Names | NR2E3 PNR RNR Photoreceptor-specific nuclear receptor Nuclear receptor subfamily 2 group E member 3 Retina-specific nuclear receptor |
| Molecular Weight(MW) | 44692 Da |
| Function | Orphan nuclear receptor of retinal photoreceptor cells. Transcriptional factor that is an activator of rod development and repressor of cone development. Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit Enhances rhodopsin expression. Represses M- and S-cone opsin expression |
| Tissue Specificity | Eye specific; found solely in the outer nuclear layer of the adult neurosensory retina, where the nuclei of cone and rod photoreceptors reside |
| Cellular Localization | Nucleus. |
| Entrez Gene | 10002 |
|---|---|
| Nucleotide Accession | NP_055064.1 NP_057430.1 |
Application
NR2E3 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the NR2E3 antibody detected the NR2E3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
