Application
NR5A2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NR5A2 antibody detected the NR5A2 protein (arrow).| Product Name | NR5A2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR5A2; B1F; CPF; FTF; Nuclear receptor subfamily 5 group A member 2; Alpha-1-fetoprotein transcription factor; B1-binding factor; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | B1F CPF FTF |
|---|---|
| Alternative Names | NR5A2 B1F CPF FTF Nuclear receptor subfamily 5 group A member 2 Alpha-1-fetoprotein transcription factor B1-binding factor CYP7A promoter-binding factor Hepatocytic transcription factor Liver receptor homolog 1 |
| Molecular Weight(MW) | 61331 Da |
| Function | Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development |
| Tissue Specificity | Abundantly expressed in pancreas, less in liver, very low levels in heart and lung. Expressed in the Hep-G2 cell line. Isoform 1 and isoform 2 seem to be present in fetal and adult liver and Hep-G2 cells |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 2494 |
|---|---|
| Nucleotide Accession | NP_003813.1 NP_995582.1 |
Application
NR5A2 Antibody (Center) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NR5A2 antibody detected the NR5A2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
