Application
NRF1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NRF1 antibody detected the NRF1 protein (arrow).| Product Name | NRF1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NRF1; Nuclear respiratory factor 1; Alpha palindromic-binding protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | NRF1 Nuclear respiratory factor 1 Alpha palindromic-binding protein |
|---|---|
| Molecular Weight(MW) | 53541 Da |
| Function | Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication |
| Tissue Specificity | Ubiquitously expressed with strongest expression in skeletal muscle |
| Cellular Localization | Nucleus. |
| Entrez Gene | 4899 |
|---|---|
| Nucleotide Accession | NP_005002.3 NP_001035199.1 |
Application
NRF1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NRF1 antibody detected the NRF1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
