Application
Western blot analysis of NSE4A Antibody (N-term) in WiDr cell line lysates (35ug/lane). NSE4A (arrow) was detected using the purified Pab.| Product Name | NSE4A Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NSMCE4A; C10orf86; Non-structural maintenance of chromosomes element 4 homolog A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C10orf86 |
|---|---|
| Alternative Names | NSMCE4A C10orf86 Non-structural maintenance of chromosomes element 4 homolog A |
| Molecular Weight(MW) | 44301 Da |
| Function | Component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT- associated PML bodies (APBs). Is involved in positive regulation of response to DNA damage stimulus |
| Tissue Specificity | This NSE4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36~65 amino acids from the N-terminal region of human NSE4A. |
| Cellular Localization | Nucleus. Chromosome, telomere (Probable). |
| Entrez Gene | 54780 |
|---|
Application
Western blot analysis of NSE4A Antibody (N-term) in WiDr cell line lysates (35ug/lane). NSE4A (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
