Application
NTAN1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the NTAN1 antibody detected the NTAN1 protein (arrow).| Product Name | NTAN1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NTAN1; Protein N-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine amidohydrolase; Protein NH2-terminal asparagine deamidase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | NTAN1 Protein N-terminal asparagine amidohydrolase Protein NH2-terminal asparagine amidohydrolase Protein NH2-terminal asparagine deamidase |
|---|---|
| Molecular Weight(MW) | 34677 Da |
| Function | Side-chain deamidation of N-terminal asparagine residues to aspartate. Required for the ubiquitin-dependent turnover of intracellular proteins that initiate with Met-Asn. These proteins are acetylated on the retained initiator methionine and can subsequently be modified by the removal of N-acetyl methionine by acylaminoacid hydrolase (AAH). Conversion of the resulting N- terminal asparagine to aspartate by PNAD renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. This enzyme does not act on substrates with internal or C-terminal asparagines and does not act on glutamine residues in any position (By similarity) |
| Tissue Specificity | This NTAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the C-terminal region of human NTAN1. |
| Cellular Localization | Cytoplasm (By similarity). |
| Entrez Gene | 123803 |
|---|---|
| Nucleotide Accession | NP_775745.1 |
Application
NTAN1 Antibody (C-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the NTAN1 antibody detected the NTAN1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
