Application
Western blot analysis of NUAK2 (arrow) using rabbit polyclonal NUAK2 Antibody (N-term) (RB08560). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NUAK2 gene (Lane 2) (Origene Technologies).| Product Name | NUAK2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | OMPHK2, SNARK |
|---|---|
| Alternative Names | NUAK2 OMPHK2 SNARK NUAK family SNF1-like kinase 2 Omphalocele kinase 2 SNF1/AMP kinase-related kinase |
| Molecular Weight(MW) | 69612 Da |
| Function | Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95- activated tumor cells. Able to phosphorylate 'Ser-464' of LATS1 |
| Tissue Specificity | This NUAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74~104 amino acids from the N-terminal region of human NUAK2. |
| Entrez Gene | 81788 |
|---|
Application
Western blot analysis of NUAK2 (arrow) using rabbit polyclonal NUAK2 Antibody (N-term) (RB08560). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the NUAK2 gene (Lane 2) (Origene Technologies).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
