Application
NUDT15 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NUDT15 antibody detected the NUDT15 protein (arrow).Application
NUDT15 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the NUDT15 antibody detected the NUDT15 protein (arrow).Application
NUDT15 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NUDT15 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
NUDT15 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | NUDT15 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MTH2 |
|---|---|
| Alternative Names | NUDT15 MTH2 Probable 8-oxo-dGTP diphosphatase NUDT15 7 8-dihydro-8-oxoguanine-triphosphatase NUDT15 MutT homolog 2 Nucleoside diphosphate-linked moiety X motif 15 |
| Molecular Weight(MW) | 18609 Da |
| Function | Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression through the interaction with PCNA |
| Tissue Specificity | This NUDT15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-118 amino acids from the C-terminal region of human NUDT15. |
| Entrez Gene | 55270 |
|---|---|
| Nucleotide Accession | NP_060753.1 |
Application
NUDT15 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NUDT15 antibody detected the NUDT15 protein (arrow).
Application
NUDT15 Antibody (C-term) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the NUDT15 antibody detected the NUDT15 protein (arrow).
Application
NUDT15 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NUDT15 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
NUDT15 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
