Application
NXN Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the NXN antibody detected the NXN protein (arrow).Application
NXN Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NXN Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | NXN Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NRX |
|---|---|
| Alternative Names | NXN NRX Nucleoredoxin |
| Molecular Weight(MW) | 48392 Da |
| Function | Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity) |
| Tissue Specificity | This NXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 220-249 amino acids from the Central region of human NXN. |
| Cellular Localization | Cytoplasm, cytosol (By similarity). Nucleus (By similarity) |
| Entrez Gene | 64359 |
|---|---|
| Nucleotide Accession | NP_071908.2 |
Application
NXN Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the NXN antibody detected the NXN protein (arrow).
Application
NXN Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NXN Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
