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OASL Antibody (C-term)

Catalog Number:OM215830
OM215830
Discount Price
OM215830-100ul
1~2 Week
100ul
OM215830-50ul
50ul
OM215830-20ul
20ul
1~2 Week
Product Profile
Product Name OASL Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms TRIP14
Alternative Names OASL
TRIP14
2'-5'-oligoadenylate synthase-like protein
2'-5'-OAS-related protein
59 kDa 2'-5'-oligoadenylate synthase-like protein
Thyroid receptor-interacting protein 14
p59 OASL
Molecular Weight(MW) 59226 Da
Function Does not have 2'-5'-OAS activity, but can bind double- stranded RNA. Displays antiviral activity against encephalomyocarditis virus (EMCV) and hepatitis C virus (HCV) via an alternative antiviral pathway independent of RNase L
Tissue Specificity Expressed in most tissues, with the highest levels in primary blood Leukocytes and other hematopoietic system tissues, colon, stomach and to some extent in testis
Cellular Localization Isoform p56: Nucleus, nucleolus. Cytoplasm.
Database Links
Entrez Gene 8638
Application

Application

The anti-OASL C-term Antibody is used in Western blot to detect OASL in HL60 lysate.

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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