Application
OCA2 Antibody (N-Term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the OCA2 antibody detected the OCA2 protein (arrow).| Product Name | OCA2 Antibody (N-Term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | D15S12, P |
|---|---|
| Alternative Names | OCA2 D15S12 P P protein Melanocyte-specific transporter protein Pink-eyed dilution protein homolog |
| Molecular Weight(MW) | 92850 Da |
| Function | Could be involved in the transport of tyrosine, the precursor to melanin synthesis, within the melanocyte. Regulates the pH of melanosome and the melanosome maturation. One of the components of the mammalian pigmentary system. Seems to regulate the post-translational processing of tyrosinase, which catalyzes the limiting reaction in melanin synthesis. May serve as a key control point at which ethnic skin color variation is determined Major determinant of brown and/or blue eye color |
| Tissue Specificity | This OCA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the N-terminal region of human OCA2. |
| Cellular Localization | Melanosome membrane; Multi-pass membrane protein |
| Entrez Gene | 4948 |
|---|---|
| Nucleotide Accession | NP_000266.2 |
Application
OCA2 Antibody (N-Term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the OCA2 antibody detected the OCA2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
