Application
Western blot analysis of OGG1 Antibody (C-term) in Hela(lane 1), NIH-3T3(lane 2) cell line lysates (35ug/lane). OGG1 (arrow) was detected using the purified Pab.| Product Name | OGG1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MMH, MUTM, OGH1 |
|---|---|
| Alternative Names | OGG1 MMH MUTM OGH1 N-glycosylase/DNA lyase 8-oxoguanine DNA glycosylase DNA-(apurinic or apyrimidinic site) lyase |
| Molecular Weight(MW) | 38782 Da |
| Function | DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N- methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta- lyase activity that nicks DNA 3' to the lesion |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Nucleus, nucleoplasm. Nucleus speckle. Nucleus matrix. Note=Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells Isoform 2A: Mitochondrion. |
| Entrez Gene | 4968 |
|---|
Application
Western blot analysis of OGG1 Antibody (C-term) in Hela(lane 1), NIH-3T3(lane 2) cell line lysates (35ug/lane). OGG1 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
