Application
Western blot analysis of OLFML3 Antibody (Center) in mouse NIH-3T3 cell line lysates (35ug/lane). OLFML3 (arrow) was detected using the purified Pab.| Product Name | OLFML3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | OLFML3 Olfactomedin-like protein 3 HNOEL-iso hOLF44 |
|---|---|
| Molecular Weight(MW) | 46010 Da |
| Function | Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes |
| Tissue Specificity | Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer |
| Cellular Localization | Secreted. |
| Entrez Gene | 56944 |
|---|
Application
Western blot analysis of OLFML3 Antibody (Center) in mouse NIH-3T3 cell line lysates (35ug/lane). OLFML3 (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
