Application
OLIG2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OLIG2 antibody detected the OLIG2 protein (arrow).| Product Name | OLIG2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BHLHB1, BHLHE19, PRKCBP2, RACK17 |
|---|---|
| Alternative Names | OLIG2 BHLHB1 BHLHE19 PRKCBP2 RACK17 Oligodendrocyte transcription factor 2 Class B basic helix-loop-helix protein 1 Class E basic helix-loop-helix protein 19 Protein kinase C-binding protein 2 Protein kinase C-binding protein RACK17 |
| Molecular Weight(MW) | 32385 Da |
| Function | Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (By similarity) |
| Tissue Specificity | Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable |
| Cellular Localization | Nucleus (By similarity). Cytoplasm (By similarity). Note=The NLS contained in the bHLH domain could be masked in the native form and translocation to the nucleus could be mediated by interaction either with class E bHLH partner protein or with NKX2-2 (By similarity) |
| Entrez Gene | 10215 |
|---|---|
| Nucleotide Accession | NP_005797.1 |
Application
OLIG2 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OLIG2 antibody detected the OLIG2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
