Application
OS9 Antibody (C-term) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the OS9 antibody detected the OS9 protein (arrow).| Product Name | OS9 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | OS9; Protein OS-9; Amplified in osteosarcoma 9 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | OS9 Protein OS-9 Amplified in osteosarcoma 9 |
|---|---|
| Molecular Weight(MW) | 75562 Da |
| Function | Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 |
| Tissue Specificity | Ubiquitously expressed. Found as well in all tumor cell lines analyzed, amplified in sarcomas. Highly expressed in osteosarcoma SJSA-1 and rhabdomyosarcoma Rh30 cell lines Isoform 2 is the major isoform detected in all cell types examined |
| Cellular Localization | Endoplasmic reticulum lumen. |
| Entrez Gene | 10956 |
|---|---|
| Nucleotide Accession | NP_001017958.1 NP_006803.1 |
Application
OS9 Antibody (C-term) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the OS9 antibody detected the OS9 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
