Application
OTOP1 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OTOP1 antibody detected the OTOP1 protein (arrow).Application
OTOP1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTOP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | OTOP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | OTOP1; Otopetrin-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | OTOP1 Otopetrin-1 |
|---|---|
| Molecular Weight(MW) | 67353 Da |
| Function | Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP (By similarity) |
| Tissue Specificity | This OTOP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-396 amino acids from the Central region of human OTOP1. |
| Cellular Localization | Membrane; Multi-pass membrane protein. Secreted, extracellular space. Note=Detected in the gelatinous membrane overlying the inner ear macular epithelium (By similarity) |
| Entrez Gene | 133060 |
|---|---|
| Nucleotide Accession | NP_819056.1 |
Application
OTOP1 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the OTOP1 antibody detected the OTOP1 protein (arrow).
Application
OTOP1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTOP1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
