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p120 Catenin Antibody

Catalog Number:OM216226
OM216226
Discount Price
OM216226-100ul
1~2 Week
100ul
OM216226-50ul
50ul
OM216226-20ul
20ul
1~2 Week
Product Profile
Product Name p120 Catenin Antibody
Antibody Type Primary Antibodies
Key Feature
Clonality Monoclonal
Clone Number EPR357(2)
Host Species Rabbit
Tested Applications WBIHCIF
WB:1:1000~10000 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms KIAA0384
Molecular Weight(MW) 108170 Da
Function Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). May associate with and regulate the cell adhesion properties of both C- and E-cadherins Implicated both in cell transformation by SRC and in ligand- induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage
Tissue Specificity Expressed in vascular endothelium.
Cellular Localization Cytoplasm. Nucleus. Cell membrane. Note=Interaction with GLIS2 promotes nuclear translocation (By similarity). Detected at cell-cell contacts. NANOS1 induces its translocation from sites of cell-cell contact to the cytoplasm
Database Links
Entrez Gene 1500
Application

Application

Western blot analysis on (A) HeLa, (B) 293T and (C) A431 cell lysates using anti-p120 Catenin RabMAb (Cat. #AJ1563c).

Application

Immunohistochemical analysis of paraffin-embedded human breast carcinoma using anti-p120 Catenin RabMAb (Cat. #AJ1563c).

Application

Immunohistochemical analysis of paraffin-embedded human colonic adenocarcinoma using anti-p120 Catenin RabMAb (Cat. #AJ1563c).

Application

Immunofluorescent staining of A431 cells using anti-p120 Catenin RabMAb (Cat. #AJ1563c).
Application Notes WB:1:1000~10000 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
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