Application
P2RX7 Antibody (C-term) western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (15ug/lane).This demonstrates the P2RX7 antibody detected the P2RX7 protein (arrow).Application
P2RX7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the P2RX7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | P2RX7 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | P2RX7; P2X purinoceptor 7; ATP receptor; P2Z receptor; Purinergic receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | P2RX7 P2X purinoceptor 7 ATP receptor P2Z receptor Purinergic receptor |
|---|---|
| Molecular Weight(MW) | 68585 Da |
| Function | Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells |
| Tissue Specificity | This P2RX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 570-600 amino acids from the C-terminal region of human P2RX7. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 5027 |
|---|---|
| Nucleotide Accession | NP_002553.2 |
Application
P2RX7 Antibody (C-term) western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (15ug/lane).This demonstrates the P2RX7 antibody detected the P2RX7 protein (arrow).
Application
P2RX7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the P2RX7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
