Application
A. Western blot analysis on HeLa cell lysate using anti-p58 RabMAb (Cat. #AJ1575a), dilution 1:5000| Product Name | p58 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DNAJC3, P58IPK, PRKRI, DnaJ homolog subfamily C member 3, Interferon-induced, double-stranded RNA-activated protein kinase inhibitor;Protein kinase inhibitor of 58 kDa;Protein kinase inhibitor p58 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP597Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:5000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | P58IPK PRKRI |
|---|---|
| Alternative Names | DNAJC3 P58IPK PRKRI DnaJ homolog subfamily C member 3 Interferon-induced double-stranded RNA-activated protein kinase inhibitor Protein kinase inhibitor of 58 kDa Protein kinase inhibitor p58 |
| Molecular Weight(MW) | 57580 Da |
| Function | Involved in the unfolded protein response (UPR) during ER stress. Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity |
| Tissue Specificity | Widely expressed with high level in the pancreas and testis. Also expressed in cell lines with different levels |
| Cellular Localization | Endoplasmic reticulum (By similarity). |
| Entrez Gene | 5611 |
|---|
Application
A. Western blot analysis on HeLa cell lysate using anti-p58 RabMAb (Cat. #AJ1575a), dilution 1:5000| Application Notes | WB:1:5000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
