Application
PACS2 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PACS2 antibody detected the PACS2 protein (arrow).Application
PACS2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PACS2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PACS2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PACS2; KIAA0602; PACS1L; Phosphofurin acidic cluster sorting protein 2; PACS1-like protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0602 PACS1L |
|---|---|
| Alternative Names | PACS2 KIAA0602 PACS1L Phosphofurin acidic cluster sorting protein 2 PACS1-like protein |
| Molecular Weight(MW) | 97702 Da |
| Function | Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments |
| Tissue Specificity | Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis |
| Cellular Localization | Endoplasmic reticulum lumen. Mitochondrion. |
| Entrez Gene | 23241 |
|---|---|
| Nucleotide Accession | NP_001094383.1 NP_056012.2 |
Application
PACS2 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the PACS2 antibody detected the PACS2 protein (arrow).
Application
PACS2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PACS2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
