Application
Western blot analysis of PAAF1 Antibody (N-term) in A549 cell line lysates (35ug/lane).PAAF1 (arrow) was detected using the purified Pab.Application
PAAF1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAAF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PAAF1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PAAF1; WDR71; Proteasomal ATPase-associated factor 1; Protein G-16; WD repeat-containing protein 71 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | WDR71 |
|---|---|
| Alternative Names | PAAF1 WDR71 Proteasomal ATPase-associated factor 1 Protein G-16 WD repeat-containing protein 71 |
| Molecular Weight(MW) | 42190 Da |
| Function | Inhibits proteasome 26S assembly and proteolytic activity by impairing the association of the 19S regulatory complex with the 20S core. In case of HIV-1 infection, recruited by viral Tat to the HIV-1 promoter, where it promotes the recruitment of 19S regulatory complex through dissociation of the proteasome 26S. This presumably promotes provirus transcription efficiency |
| Tissue Specificity | Ubiquitously expressed, with highest levels in kidney, brain and testis |
| Entrez Gene | 80227 |
|---|
Application
Western blot analysis of PAAF1 Antibody (N-term) in A549 cell line lysates (35ug/lane).PAAF1 (arrow) was detected using the purified Pab.
Application
PAAF1 Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAAF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
