Application
Western blot analysis of anti-Pael-R (GPR37) Pab in mouse brain tissue lysate. Pael-R (GPR37) (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.Application
Pael Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Pael antibody detected the Pael protein (arrow).| Product Name | Pael-R (GPR37) Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GPR37; Probable G-protein coupled receptor 37; Endothelin B receptor-like protein 1; Parkin-associated endothelin receptor-like receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | GPR37 Probable G-protein coupled receptor 37 Endothelin B receptor-like protein 1 Parkin-associated endothelin receptor-like receptor |
|---|---|
| Molecular Weight(MW) | 67114 Da |
| Function | Orphan receptor. May have a unique functional role in the central nervous system |
| Tissue Specificity | Expressed in brain and spinal cord, and at lower levels in testis, placenta and liver, but no detectable expression observed in any other tissue. When overexpressed in cells, tends to become insoluble and unfolded. Accumulation of the unfolded protein may lead to dopaminergic neuronal death in juvenile Parkinson disease (PDJ) |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein |
Application
Western blot analysis of anti-Pael-R (GPR37) Pab in mouse brain tissue lysate. Pael-R (GPR37) (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application
Pael Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the Pael antibody detected the Pael protein (arrow).| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
