Application
The anti-PAPSS2 Pab is used in Western blot to detect PAPSS2 in Jurkat cell lysate.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.| Product Name | PAPSS2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PAPSS2; ATPSK2; Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2; Sulfurylase kinase 2; Sulfate adenylyltransferase; ATP-sulfurylase; Sulfate adenylate transferase; Adenylyl-sulfate kinase; 3'-phosphoadenosine-5'-phosphosulfate synthase; APS k |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ATPSK2 |
|---|---|
| Alternative Names | PAPSS2 ATPSK2 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 Sulfurylase kinase 2 Sulfate adenylyltransferase ATP-sulfurylase Sulfate adenylate transferase Adenylyl-sulfate kinase 3'-phosphoadenosine-5'-phosphosulfate synthase APS k |
| Molecular Weight(MW) | 69501 Da |
| Function | Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. May have a important role in skeletogenesis during postnatal growth (By similarity) |
| Tissue Specificity | Expressed in cartilage and adrenal gland. |
| Entrez Gene | 9060 |
|---|---|
| Nucleotide Accession | NP_001015880 |
Application
The anti-PAPSS2 Pab is used in Western blot to detect PAPSS2 in Jurkat cell lysate.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
