Application
Western blot analysis of PARD6A Antibody (Center) in CEM cell line lysates (35ug/lane).PARD6A (arrow) was detected using the purified Pab.Application
PARD6A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PARD6A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PARD6A Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PARD6A; PAR6A; Partitioning defective 6 homolog alpha; PAR6C; Tax interaction protein 40 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PAR6A |
|---|---|
| Alternative Names | PARD6A PAR6A Partitioning defective 6 homolog alpha PAR6C Tax interaction protein 40 |
| Molecular Weight(MW) | 37388 Da |
| Function | Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins |
| Tissue Specificity | Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta |
| Cellular Localization | Cytoplasm. Cell membrane. Cell projection, ruffle. Cell junction, tight junction. Note=Colocalizes with GTP- bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions |
| Entrez Gene | 50855 |
|---|
Application
Western blot analysis of PARD6A Antibody (Center) in CEM cell line lysates (35ug/lane).PARD6A (arrow) was detected using the purified Pab.
Application
PARD6A Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PARD6A Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
