Application
PARP2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PARP2 antibody detected the PARP2 protein (arrow).| Product Name | PARP2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Parp2; Adprt2; Adprtl2; Aspartl2; Poly [ADP-ribose] polymerase 2; ADP-ribosyltransferase diphtheria toxin-like 2; NAD(+) ADP-ribosyltransferase 2; Poly[ADP-ribose] synthase 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Adprt2 Adprtl2 Aspartl2 |
|---|---|
| Alternative Names | Parp2 Adprt2 Adprtl2 Aspartl2 Poly [ADP-ribose] polymerase 2 ADP-ribosyltransferase diphtheria toxin-like 2 NAD(+) ADP-ribosyltransferase 2 Poly[ADP-ribose] synthase 2 |
| Molecular Weight(MW) | 63397 Da |
| Function | Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks |
| Tissue Specificity | Widely expressed; the highest levels were in testis followed by ovary. Expression is correlated with proliferation, with higher levels occurring during early fetal development and organogenesis and in the highly proliferative cell compartments of adult |
| Cellular Localization | Nucleus. |
| Entrez Gene | 11546 |
|---|---|
| Nucleotide Accession | NP_033762.1 |
Application
PARP2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PARP2 antibody detected the PARP2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
