Application
Western blot analysis of PARVA Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). PARVA (arrow) was detected using the purified Pab.Application
PARVA Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PARVA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PARVA Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PARVA; MXRA2; Alpha-parvin; Actopaxin; CH-ILKBP; Calponin-like integrin-linked kinase-binding protein; Matrix-remodeling-associated protein 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MXRA2 |
|---|---|
| Alternative Names | PARVA MXRA2 Alpha-parvin Actopaxin CH-ILKBP Calponin-like integrin-linked kinase-binding protein Matrix-remodeling-associated protein 2 |
| Molecular Weight(MW) | 42244 Da |
| Function | Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development (By similarity) Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration |
| Tissue Specificity | Widely expressed, with highest levels in heart, skeletal muscle, kidney and liver |
| Cellular Localization | Cell junction, focal adhesion. Cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line (By similarity). Note=Constituent of focal adhesions. Associates with the actin cytoskeleton |
| Entrez Gene | 55742 |
|---|
Application
Western blot analysis of PARVA Antibody (C-term) in mouse bladder tissue lysates (35ug/lane). PARVA (arrow) was detected using the purified Pab.
Application
PARVA Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded human skeletal muscle tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PARVA Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
