Application
A. Western blot analysis on HeLa cell lysate using anti-PBK RabMAb (Cat. #AJ1593a), dilution 1:100,000.| Product Name | PBK (TOPK) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PBK, TOPK, Lymphokine-activated killer T-cell-originated protein kinase, MAPKK-like protein kinase;Nori-3;Cancer/testis antigen 84 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP2519Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50000~100000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TOPK |
|---|---|
| Alternative Names | PBK TOPK Lymphokine-activated killer T-cell-originated protein kinase MAPKK-like protein kinase Nori-3 Cancer/testis antigen 84 |
| Molecular Weight(MW) | 36085 Da |
| Function | Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage |
| Tissue Specificity | Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules |
| Entrez Gene | 55872 |
|---|
Application
A. Western blot analysis on HeLa cell lysate using anti-PBK RabMAb (Cat. #AJ1593a), dilution 1:100,000.| Application Notes | WB:1:50000~100000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
