Application
Western blot analysis of anti-PPBP Pab in CEM cell line lysates (35ug/lane). PPBP(arrow) was detected using the purified Pab (1:60 dilution).Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PPBP antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | PBP (PPBP) Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPBP; CTAP3; CXCL7; SCYB7; TGB1; THBGB1; Platelet basic protein; C-X-C motif chemokine 7; Leukocyte-derived growth factor; Macrophage-derived growth factor; Small-inducible cytokine B7; Connective tissue-activating peptide III; LA-PF4; Low-affinity platele |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CTAP3 CXCL7 SCYB7 TGB1 THBGB1 |
|---|---|
| Alternative Names | PPBP CTAP3 CXCL7 SCYB7 TGB1 THBGB1 Platelet basic protein C-X-C motif chemokine 7 Leukocyte-derived growth factor Macrophage-derived growth factor Small-inducible cytokine B7 Connective tissue-activating peptide III LA-PF4 Low-affinity platele |
| Molecular Weight(MW) | 13894 Da |
| Function | LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation |
| Tissue Specificity | This PBP (PPBP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99~128 amino acids from the C-term of human PPBP. |
| Cellular Localization | Secreted. |
| Entrez Gene | 5473 |
|---|
Application
Western blot analysis of anti-PPBP Pab in CEM cell line lysates (35ug/lane). PPBP(arrow) was detected using the purified Pab (1:60 dilution).
Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PPBP antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
