Application
PC Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PC antibody detected the PC protein (arrow).Application
PC Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PC Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PC Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PC; Pyruvate carboxylase, mitochondrial; Pyruvic carboxylase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PC Pyruvate carboxylase mitochondrial Pyruvic carboxylase |
|---|---|
| Molecular Weight(MW) | 129634 Da |
| Function | Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate |
| Tissue Specificity | This PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human PC. |
| Cellular Localization | Mitochondrion matrix. |
| Entrez Gene | 5091 |
|---|---|
| Nucleotide Accession | NP_001035806.1 NP_000911.2 |
Application
PC Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PC antibody detected the PC protein (arrow).
Application
PC Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PC Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
