Application
PCBP2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PCBP2 antibody detected the PCBP2 protein (arrow).Application
PCBP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PCBP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
PCBP2 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | PCBP2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PCBP2; Poly(rC)-binding protein 2; Alpha-CP2; Heterogeneous nuclear ribonucleoprotein E2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PCBP2 Poly(rC)-binding protein 2 Alpha-CP2 Heterogeneous nuclear ribonucleoprotein E2 |
|---|---|
| Molecular Weight(MW) | 38580 Da |
| Function | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation |
| Tissue Specificity | Detected in all tissues examined. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm |
| Entrez Gene | 5094 |
|---|---|
| Nucleotide Accession | NP_001122383.1 |
Application
PCBP2 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PCBP2 antibody detected the PCBP2 protein (arrow).
Application
PCBP2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PCBP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
PCBP2 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
