Application
Western blot analysis of PCSK2 Antibody (Center) in 293(lane 1), K562(lane 2) cell line lysates (35ug/lane). PCSK2 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with PCSK2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
PCSK2 Antibody (Center) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | PCSK2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PCSK2; NEC2; Neuroendocrine convertase 2; KEX2-like endoprotease 2; Prohormone convertase 2; Proprotein convertase 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NEC2 |
|---|---|
| Alternative Names | PCSK2 NEC2 Neuroendocrine convertase 2 KEX2-like endoprotease 2 Prohormone convertase 2 Proprotein convertase 2 |
| Molecular Weight(MW) | 70565 Da |
| Function | Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells |
| Tissue Specificity | This PCSK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325~355 amino acids from the Center region of human PCSK2. |
| Cellular Localization | Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules |
| Entrez Gene | 5126 |
|---|
Application
Western blot analysis of PCSK2 Antibody (Center) in 293(lane 1), K562(lane 2) cell line lysates (35ug/lane). PCSK2 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with PCSK2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
PCSK2 Antibody (Center) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
