PDCD10 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PDCD10 antibody detected the PDCD10 protein (arrow).
PDCD10; CCM3; TFAR15; Programmed cell death protein 10; Cerebral cavernous malformations 3 protein; TF-1 cell apoptosis-related protein 15
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CCM3 TFAR15
Alternative Names
PDCD10 CCM3 TFAR15 Programmed cell death protein 10 Cerebral cavernous malformations 3 protein TF-1 cell apoptosis-related protein 15
Molecular Weight(MW)
24702 Da
Function
Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and MST4 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity)
Tissue Specificity
Ubiquitous.
Cellular Localization
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Partially co- localizes with endogenous PXN at the leading edges of migrating cells
PDCD10 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the PDCD10 antibody detected the PDCD10 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.