Application
PDCD1LG2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDCD1LG2 antibody detected the PDCD1LG2 protein (arrow).Application
PDCD1LG2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PDCD1LG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | PDCD1LG2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDCD1LG2; B7DC; CD273; PDCD1L2; PDL2; Programmed cell death 1 ligand 2; Butyrophilin B7-DC; CD_antigen=CD273; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | B7DC CD273 PDCD1L2 PDL2 |
|---|---|
| Alternative Names | PDCD1LG2 B7DC CD273 PDCD1L2 PDL2 Programmed cell death 1 ligand 2 Butyrophilin B7-DC CD_antigen=CD273 Flags: Precursor |
| Molecular Weight(MW) | 30957 Da |
| Function | Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) |
| Tissue Specificity | Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus |
| Cellular Localization | Isoform 3: Secreted (Probable). Isoform 1: Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 80380 |
|---|---|
| Nucleotide Accession | NP_079515.2 |
Application
PDCD1LG2 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PDCD1LG2 antibody detected the PDCD1LG2 protein (arrow).
Application
PDCD1LG2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PDCD1LG2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
