Application
Western blot analysis of PDE8A Antibody (Center) (L572) (Cat# AP1463c) in HL60 cell line lysates (35ug/lane). PDE8A (arrow) was detected using the purified Pab (1:60 dilution).Application
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PDE8A antibody (Center) (L572), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | PDE8A Antibody (Center) (L572) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDE8A; High affinity cAMP-specific and IBMX-insensitive 3', 5'-cyclic phosphodiesterase 8A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PDE8A High affinity cAMP-specific and IBMX-insensitive 3' 5'-cyclic phosphodiesterase 8A |
|---|---|
| Molecular Weight(MW) | 93304 Da |
| Function | Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development |
| Tissue Specificity | Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon |
| Entrez Gene | 5151 |
|---|
Application
Western blot analysis of PDE8A Antibody (Center) (L572) (Cat# AP1463c) in HL60 cell line lysates (35ug/lane). PDE8A (arrow) was detected using the purified Pab (1:60 dilution).
Application
Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PDE8A antibody (Center) (L572), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
